Marc Masson graduated as pianist under Claude Coppens with the greatest distinction. He also studied harmony, counterpoint and fugue with Anna-Maria Van Haute. He received several prizes, including the Bach Prize from the Academy of Performing Arts (Aalst) and the board prize from De Link (Tilburg) for "Best Performance of Contemporary Music". He participated in masterclasses by Rainer Schmidt, Rudolf Jansen, Willem Brons, Robert Holl, Meinaard Kraak, Jard van Nes, Justus Grimm, Ulrich Eisenlohr, Mathis Dulack, Salvador Mas Conde and Jörg Bierhance.

Under the inspiring leadership of Michaël Ghijs he accompanied the Schola Cantorum Cantate Domino, with which he performed all over Belgium and abroad (including South Korea, Argentina, Portugal, Japan, Israel, South Africa, etc.). As pianist of the Ghent University Choir he gave concerts in New York, Bratislava, Valencia... 

Marc Masson performed in 'The House of Composers' (St. Petersburg), the Concertgebouw (Bruges), the Handelsbeurs (Ghent), the Bijloke (Ghent), Christ College (Cambridge), the Belgian Embassy (London) and the Koninklijke Muntschouwburg (Brussels)... During the Festival of Wallonia, together with Ex Tempore (conducted by Florian Heyerick), he performed 'Der Rose Pilgerfahrt' by Robert Schumann.

He teaches piano at the Stedelijke Academie voor Muziek, Woord en Dans (Urban Academy for Music, Word and Dance) in Deinze.